DOSAGE AND ADMINISTRATION:
Carbinoxamine maleate is contraindicated in children younger than 2 years of age (see CONTRAINDICATIONS).
Carbinoxamine maleate should be taken on an empty stomach with water.
DOSAGE SHOULD BE INDIVIDUALIZED ACCORDING TO THE NEEDS AND THE RESPONSE OF THE PATIENT.
Carbinoxamine maleate dosage should be based on the severity of the condition and the response of the patient. The drug is well tolerated in doses as high as 24 mg daily, in divided doses, over prolonged periods. On the other hand, many patients respond to as little as a 4mg tablet or 4mg/5mL liquid dose to enjoy a symptom-free, active day. The primary side effect is a 15-20% sedation rate.
Clinical experience suggests the following dosage schedules:
Tablets
- Usual Adult Dosage:
- 1 or 2 tablets (4 to 8 mg) 3 to 4 times daily
- Usual Child's Dosage:
- Over six years - 1 to 1½ tablets (4 to 6 mg) 3 or 4 times daily.
Oral Solution
- Usual Adult Dosage:
- 1 or 2 teaspoonfuls (4 to 8 mg) 3 to 4 times daily
- Usual Child's Dosage (approximately 0.2 - 0.4 mg/kg/day):
- Two to three years - ½ teaspoonful (2 mg) 3 or 4 times daily.
- Three to six years - ½ teaspoonful to 1 teaspoonful (2 to 4 mg) 3 or 4 times daily
- Over six years - 1 to 1½ teaspoonfuls (4 to 6 mg) 3 or 4 times daily.
